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检索条件"机构=Tianjin 300071"
29961 条 记 录,以下是1-10 订阅
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Dulcitol suppresses proliferation and migration of hepatocellular carcinoma via regulating SIRT1/p53 pathway
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Phytomedicine 2020年 66卷
作者: Xiao lin Lin Kai Li Zhuo Yang Baogui Chen Tao Zhang College of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine 301617 Tianjin PR China School of Medicine Nankai University 300071 Tianjin PR China WuQing TCM hospital Affiliated to Tianjin University of Traditional Chinese Medicine 301700 Tianjin PR China College of Life Sciences and Key Laboratory of Bioactive Materials Ministry of Education Nankai University Tianjin 300071 PR China
Background Hepatocellular carcinoma (HCC) spreads further with continuance and increasing incidence due to its high-grade malignancy and metastasis. More effectual strategies on blocking proliferation and metastasis o... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach
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European journal of medicinal chemistry 2020年 187卷
作者: Yu Wei Mukuo Wang Yang Li Zhangyong Hong Dongmei Li Jianping Lin State Key Laboratory of Medicinal Chemical Biology College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research Nankai University Haihe Education Park 38 Tongyan Road Tianjin 300353 China State Key Laboratory of Medicinal Chemical Biology College of Life Sciences Nankai University 94 Weijin Road Tianjin 300071 China Biodesign Center Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences 32 West 7th Avenue Tianjin Airport Economic Area Tianjin 300308 China Platform of Pharmaceutical Intelligence Tianjin International Joint Academy of Biomedicine Tianjin 300457 China
Highlights New antagonists against A1AR identified by a multistage virtual screening. 18 new compounds exhibited nanomolar or low micromolar binding potency. Four of six compounds (pKi > 6) were highly selective... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Regional and sustained dual-release of growth factors from biomimetic tri-layered scaffolds for the repair of large-scale osteochondral defects
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Applied Materials Today 2020年 19卷
作者: Yunsheng Dong Xun Sun Zhiling Zhang Yufei Liu Lin Zhang Xiangyun Zhang Ying Huang Yanhong Zhao Chunxiao Qi Adam C. Midgley Shufang Wang Qiang Yang State Key Laboratory of Medicinal Chemical Biology The Key Laboratory of Bioactive Materials The College of Life Science Nankai University Tianjin 300071 China Department of Spine Surgery Tianjin Hospital Tianjin 300211 China Tianjin Stomatological Hospital Tianjin 300041 China Stomatological Hospital of Tianjin Medical University Tianjin 300070 China
Highlights Tri-layered scaffolds with mimicking osteochondral structure. Tri-layered scaffolds were functionalized to provide local and sustained release of double growth factors. The ability of hUCMSCs to diffe... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Photo-luminescent chiral carbon-dot@Eu(D-cam) nanocomposites for selectively luminescence sensing of l-phenylalanine
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Journal of molecular structure 2020年 1201卷
作者: Jian Zhong Huo Xin Shu Li Jun Dan An Le Xi Zhang Yong Li Gui Xiang Du Xiang Xia Wu Yuan Yuan Liu Bin Ding Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry (Tianjin Normal University) Ministry of Education Tianjin Key Laboratory of Structure and Performance for Functional Molecule College of Chemistry Tianjin Normal University 393 Binshui West Road Tianjin 300387 PR China Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) College of Chemistry Nankai University Tianjin 300071 PR China School of Materials Science and Engineering Tianjin University of Technology Tianjin 300384 China Tianjin Normal University 393 Binshui West Road Tianjin 300387 PR China
Highlights A novel photo-luminescent chiral [email protected](D-Cam) nano-composites has been synthesized. The as-prepared fluorescent probe exhibited excellent optical properties and solvent-stability. The [ema... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Co-localized delivery of nanomedicine and nanovaccine augments the postoperative cancer immunotherapy by amplifying T-cell responses
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Biomaterials 2020年 230卷
作者: Xiang Liu Zujian Feng Changrong Wang Qi Su Huijuan Song Chuangnian Zhang Pingsheng Huang Xing-Jie Liang Anjie Dong Deling Kong Weiwei Wang Department of Polymer Science and Engineering Key Laboratory of Systems Bioengineering (Ministry of Education) School of Chemical Engineering and Technology Tianjin University Tianjin 300072 China Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin 300072 China Tianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering Chinese Academy of Medical Sciences and Peking Union Medical College Tianjin 300192 China Key Laboratory for Biological Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology Chinese Academy of Sciences Beijing 100190 China State Key Laboratory of Medicinal Chemical Biology College of Life Sciences Nankai University Tianjin 300071 China
Immunotherapy in solid tumors is limited by the poor immunogenicity of tumors and limited T-cell immune response, resulting in low patient response rate. To increase the efficiency of cancer immunotherapy, a unique sy... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Enhanced photocatalytic activity for tetracyclines degradation with Ag modified g-C3N4 composite under visible light
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Journal of Photochemistry and Photobiology A: Chemistry 2020年 389卷
作者: Zequn Ren Fangyuan Chen Kangxin Wen Jinfeng Lu College of Environmental Science and Engineering Nankai University Tianjin 300071 China Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution Tianjin 300071 China Key Laboratory of Pollution Processes and Environmental Criteria (Nankai University) Ministry of Education Tianjin 300071 China
Highlights Novel Ag/g-C3N4 composites were prepared via thermal polymerization associated with photo-deposition methods. The as-prepared Ag/g-C3N4 composites showed improved photocatalytic performance towards TCs.... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Combined treatment of melatonin and sodium tanshinone IIA sulfonate reduced the neurological and cardiovascular toxicity induced by deltamethrin in zebrafish
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Chemosphere 2020年 243卷
作者: Meng Li Ti Zhang YiQing Jia YuMeng Sun ShaoZhi Zhang Ping Mi ZeYang Feng Xin Zhao DongYan Chen XiZeng Feng State Key Laboratory of Medicinal Chemical Biology The Key Laboratory of Bioactive Materials Ministry of Education College of Life Science Nankai University Tianjin 300071 China Tianjin Key Laboratory of Tumor Microenvironment and Neurovascular Regulation Department of Histology and Embryology School of Medicine Nankai University Tianjin 300071 China The Institute of Robotics and Automatic Information Systems College of Artificial Intelligence Nankai University Tianjin 300071 China
Highlights Cardiovascular and neuroprotective effects of STS and MT on zebrafish larvae. DM causes heart and vessel morphology and functional damage, affecting sleep-waking. Heart beat amplitude to evaluate card... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Photoelectrochemical degradation of 2,4-dichlorophenoxyacetic acid using electrochemically self-doped Blue TiO2 nanotube arrays with formic acid as electrolyte
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Journal of hazardous materials 2020年 382卷
作者: Xin Xu Jingju Cai Minghua Zhou Xuedong Du Ying Zhang Key Laboratory of Pollution Process and Environmental Criteria Ministry of Education College of Environmental Science and Engineering Nankai University Tianjin 300071 China Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution College of Environmental Science and Engineering Nankai University Tianjin 300071 China Tianjin Advanced Water Treatment Technology International Joint Research Center College of Environmental Science and Engineering Nankai University Tianjin 300350 China
Highlights Blue-TNTs exhibited much stronger light-absorption than intact TNTs. A significant synergetic effect of EC and PC was observed in PEC with Blue-TNTs. The PEC degradation of 2,4-D using Blue-TNTs was m... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Hypoxia-tropic nanozymes as oxygen generators for tumor-favoring theranostics
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Biomaterials 2020年 230卷
作者: Fangli Gao Jin Wu Heqi Gao Xueyan Hu Lihua Liu Adam C. Midgley Qiqi Liu Zhiyuan Sun Yijin Liu Dan Ding Yanming Wang Deling Kong Xinglu Huang Key Laboratory of Bioactive Materials Ministry of Education College of Life Sciences and State Key Laboratory of Medicinal Chemical Biology Nankai University Tianjin 300071 China Department of Radiology Tianjin First Central Hospital Tianjin 300192 China State Key Laboratory of Medicinal Chemical Biology College of Pharmacy Nankai University Tianjin 300353 China Joint Laboratory of Nanozymes College of Life Sciences Nankai University Tianjin 300071 China
Oxygen deficiency is the main obstacle of hypoxia-related theranostics, thus this is a considerable amount of research focusing on the development of methods to supply oxygen by taking advantage of hypoxia-responsive ... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论
Malus micromalus Makino phenolic extract preserves hepatorenal function by regulating PKC-α signaling pathway and attenuating endoplasmic reticulum stress in lead (II) exposure mice
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Journal of inorganic biochemistry 2020年 203卷
作者: Guangliang Wang Jinlei Tang Qi Song Qianqian Yu Congying Yao Pengfei Li Yixin Ding Mibin Lin Dai Cheng State Key Laboratory of Food Nutrition and Safety Tianjin University of Science & Technology,Tianjin 300457China Demonstration center of food quality and safety testing technology Tianjin University of Science and Technology 300457 Tianjin China Tianjin Key Laboratory of Food Science and Health School of Medicine Nankai University Tianjin 300071 China
Highlights Malus micromalus Makino phenolic extract (MMPE) was identified and quantified. MMPE could maintain the integrity of erythrocyte membranes in Pb-treated mice. MMPE could effectively suppress the disord... 详细信息
来源: ElsevierScienceDirect期刊 ElsevierScienceDirec... 评论