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A model of malignant risk prediction for solitary pulmonary nodules on 18F-FDG PET/CT:building and estimating

A model of malignant risk prediction for solitary pulmonary nodules on 18F-FDG PET/CT:building and estimating

作     者:程远 CHENG Yuan(PET/CT Center,Affil Hosp,Qingdao Univ,Qingdao 266100)

作者机构:PET/CT CenterAffil HospQingdao UnivQingdao 266100 

出 版 物:《中国医学文摘:内科学分册(英文版)》 (中国医学文摘(内科学分册)(英文版))

年 卷 期:2019年第2期

页      面:102-102

学科分类:1002[医学-临床医学类] 1002[医学-临床医学类] 1002[医学-临床医学类] 

主  题:SUVmax PET F-FDG PET/CT:building and estimating FDG A model of malignant risk prediction for solitary pulmonary nodules on 

摘      要:Objective To develop a model of malignant risk predictionof solitary pulmonary nodules ( SPN) with themetabolic characteristics of the lesion. Methods A totalof 362 patients (291 malignant cases and 71 benign cases;194 males,168 females;median age: 61 years)who underwent PET /CT imaging from January 2013 toJuly 2017 were analyzed. The diagnosis of malignantSPN was based on pathological results,and that of benignSPN was based on pathological or follow-up results.Differences of clinical /imaging characteristics in patientswith benign and those with malignant SPN were analyzed.Risk factors were screened by multivariate nonconditionallogistic regression analysis. The self-verificationof the model was done by the receiver operatingcharacteristic (ROC) curve analysis,out-of-group verificationwas performed by k-fold cross-validation.

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